Polynucleotides
A focus on skin texture, hydration and elasticity.
Noticing fine lines, changes in texture or skin that feels less hydrated? You may be curious about exploring treatments that could help your skin look and feel refreshed.
At MediSkin by SMG, polynucleotide treatments focus on skin quality, aiming to soften the appearance of fine lines and support hydration and elasticity.
Led by Independent Nurse Prescriber Sophie Gordon, our approach combines clinical knowledge with personal care, keeping your individual needs and natural features at the heart of every recommendation.
Based in Long Eaton, we welcome patients from Nottingham, Derby and across the East Midlands.
What are polynucleotides treatments?
Polynucleotides are purified fragments of DNA, commonly derived from salmon or trout, used in injectable treatments aimed at improving skin quality.
Unlike dermal fillers, which are primarily used to add volume or contour, polynucleotide treatments focus on the condition of the skin itself, with changes developing gradually.
What Can polynucleotides Help With?
Depending on your skin and the area being treated, polynucleotides may help improve:
Fine lines softening their appearance.
Dryness and dehydration supporting skin hydration.
Uneven texture encouraging smoother-looking skin.
Crepey-looking skin improving the appearance of delicate texture and elasticity.
Under-eye skin quality addressing selected concerns involving fine lines and thin, crepey-looking skin.
Suitability and results vary. Sophie will assess your concerns and explain what treatment may realistically offer as part of your personalised plan.
Polynucleotides for the under-eye area
The delicate skin around your eyes can be one of the first places you notice fine lines or a crepey-looking texture. Under-eye polynucleotide treatments focus on skin quality, with the aim of supporting hydration, elasticity and a smoother-looking appearance.
Every under-eye concern deserves an individual approach. Whether you’re noticing dark circles, hollows or changes in texture, understanding what’s contributing to them helps us recommend suitable care. Polynucleotides may be considered where skin quality is the focus, while concerns involving volume or eye bags may benefit from a different approach.
Your polynucleotides Appointment at MediSkin
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Your consultation is time to discuss what you’ve noticed, explore your goals and ask questions. Sophie will assess your skin and review your medical history to determine whether polynucleotide treatment is suitable.
Together, you’ll discuss the proposed treatment area, potential benefits, risks, costs and a recommended plan, with time to consider your options.
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We’ll explain each step and make time for you to feel comfortable. Your practitioner will prepare the treatment area and administer the polynucleotides through a series of small injections, using appropriate comfort measures.
Before you leave, we’ll talk you through what to expect as your skin settles and provide personalised aftercare guidance.
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Our support continues beyond your appointment. You’ll receive clear advice on caring for the treated area and how to contact us with any concerns.
Follow-up allows us to review your response and discuss the next steps in your plan, including any further sessions recommended around your individual needs.
Your mediskin journey, starts here.
We look forward to getting to know you and your goals. Choose a consultation time that suits you below.

